Acarbose API

Product Name: Acarbose
Origin: China
Supply Ability: 1ton per month
Sample Available: Yes
Shelf Life: Two years
Payment: T/T, LC or DA
Certifications: ISO9001, ISO22000, HACCP, HALAL, KOSHER
Third Party Test: available
Plant Audition: available
Can’t sell to individuals
  • Fast Delievery
  • Quality Assurance
  • 24/7 Customer Service
Product Introduction

Acarbose API Supplier

Xi'an Yihui Company is a professional manufacturer of Acarbose. We can generate Acarbose with a 99.9% content. It can be utilized in food,medicine, health care items, or cosmetics products, and meet USP, BP, EP,CP standards. We can offer you products of the highest caliber at the most competitive rates. Your best option for a reputable pure Acarbose supplier is Xi'an Yihui Company!

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What is Acarbose API?

Acarbose API, an organic compound with the chemical formula C25H43NO18 and CAS No. 56180-94-0.It is a white or white-like, crystalline powder, odorless, slightly bitter, water-soluble. The chemical name of acarbose is 4, 6-o-ethyl mannitol-keto-alpha-d-glucose.

Acarbose API is an active ingredient of alpha-glucosidase inhibitor drugs, usually produced in industry by microbial fermentation, such as actinomyces. The production process mainly includes microbial culture, cell isolation and purification, reactor feeding reaction and extraction, product separation and purification, and other steps, among which reactor feeding reaction is the core step to prepare carboxylate from glucose. It is primarily used to treat type 2 diabetes.


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Basic Information

Appearance

white or yellowish, amorphous powder

Structural formula

Molecular Formula

C25H43NO18

Melting point

165 to 170 ℃

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Formula Weight

645.61

Boiling point

971.6 ℃

CAS No.

56180-94-0

Density

1.74 g/cm ³

Purity

min 98%

storage temp.

Room temp.

Quality standard

Items

Specifications

Results

Characters

White or yellowish, amorphous powder, hygroscopic. Very soluble in water, soluble in methanol, practically insoluble in methylene chloride

Conforms

Identification

As per EP10.0

Conforms

Absorbance

Max. 0.15 at 425nm for solution S.

0.001

Assay (on anhydrousbasis)

95.0%~102.0%

99.3%

Water

≤4.0%

1.8%

Specific optical rotation

+168°~+183°

+181°

Sulfated ash

≤0.2%

0.06%

PH

5.5~7.5

6.6

Heavy metals

≤20ppm

Conforms


               


               


               

Related substance

Impurity A Max 0.6%

0.2%

Impurity B Max 0.5%

0.2%

Impurity C Max 1.5%

0.2%

Impurity D Max 1.0%

0.3%

Impurity E Max 0.2%

Negative

Impurity F Max 0.3%

Negative

Impurity G Max 0.3%

Negative

Any other impurity each impurities Max 0.2%

Conforms

Total impurities Max 3.0%

1.1%

Conclusion: this product complies with the specifications of EP10.0.

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What Is Acarbose Used For?

Acarbose API is a popular drug that's primarily used to treat type 2 diabetes. Specifically, it's classified as a nascence- glucosidase asset and acts on the small intestine to decelerate down the breakdown and immersion of carbohydrates. This drug is generally specified as an adjunct to diet and exercise and is frequently used in combination with other diabetes specifics.

it works by inhibiting the enzymes that typically break down complex carbohydrates into simple sugars, similar as glucose. By decelerating down the digestion and immersion of these sugars, it helps to control blood sugar situations in people with diabetes. This can help to help complications and ameliorate overall health issues.

In addition to treating type 2 diabetes, it has also been studied for its implicit use in reducing the threat of heart complaints and other cardiovascular complications. Some exploration has suggested that this drug may help to ameliorate lipid biographies and reduce inflammation in the body, which could lead to a reduced threat of heart complaints over time.

Other implicit its uses may include the treatment of other conditions associated with insulin resistance, similar as polycystic ovary pattern( PCOS) and metabolic pattern. still, further exploration is demanded before these implicit uses can be completely understood.

Overall, it's an important drug for the treatment of type 2 diabetes and other affiliated conditions. By decelerating carbohydrate immersion and helping to control blood sugar situations, this drug can help to reduce the threat of complications and ameliorate overall health outcomes. However, talk to your croaker about whether it may be a good treatment option for you, If you have been diagnosed with type 2 diabetes or another affiliated condition.

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Preparation

The synthesis process of Acarbose can be summarized into the following three steps:

  1. Synthesis of aminocyclitol: Sedoheptulose-7-phosphate undergoes a series of enzymatic responses including intramolecular cyclization, epimerization, dehydrogenation, dehumidification, phosphorylation, and nucleotidylation to produce NDP-1-epi-valienol-7-phosphate.

  2. Synthesis of 4-amino-4,6-dideoxyglucose:D- glucose-1-phosphate is converted into dTDP through nucleotidylation, dehumidification, and transamination.

  3. Synthesis of acarviosyl moiety: NDP-1-epi-valienol-7-phosphate and dTDP suffer sugar transfer response intermediated by glycosyltransferase to form dTDP- acarbose-7-phosphate, which also directly combines with maltose to induce acarbose-7-phosphate. Acarbose-7-phosphate is synthesized inside the cell, but to finally produce acarbose, it needs to be transported outside the cell via the transmembrane protein AcbWXY/GacWXY and undergo dephosphorylation.

What Is Side Effects For Acarbose?

Acarbose is a drug used in the treatment of type 2 diabetes. While this drug is effective in controlling blood sugar situations, it also has several given side goods which may be concerning for cases. Some of the most common side goods of Acarbose anti aging are mentioned below

1. Stomach problems:It can beget bloating, gas, and diarrhea. These digestive problems can be particularly worrisome for cases who are formerly dealing with gastrointestinal issues.

2. Low blood sugar: It can beget hypoglycemia, which is characterized by low blood sugar situations. Cases taking this drug should be apprehensive of the signs and symptoms of hypoglycemia and should consume a regular, balanced diet to avoid this side effect.

3. Liver problems: It can beget liver damage in rare cases. Cases taking this drug should have their liver function covered regularly.

4. Skin rash: Some cases may develop a rash while taking it. While this symptom is generally mild, cases should notify their croaker if they witness any new or unusual skin changes.

5. Allergic reactions: Some cases may witness an antipathetic response to acarbose. Symptoms may include difficulty breathing, hives, or swelling of the face and throat. Cases should seek medical attention incontinently if they witness any of these symptoms.

6. Flatulence: It has been known to cause increased flatulence or the passing of gas. This symptom may be distressing for some patients but is generally not harmful.
7. Interference with nutrient absorption: It may interfere with the absorption of certain nutrients, such as calcium and vitamin D. Patients taking this medication should consume a diet rich in these nutrients or take a supplement to avoid deficiencies.
It is important for patients taking acarbose to be aware of these potential side effects and to discuss any concerns with their doctor. If any of these symptoms become severe or persistent, patients should seek medical attention immediately. Overall, acarbose is a useful medication for controlling blood sugar levels in patients with type 2 diabetes, but it is important to be aware of the potential side effects.

Packing & Shipping

Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.

Customization: Customized logo; Customized packaging; Graphic customization

Shipping:

Item

Quantity

ETA time

Shipping Method

By Courier

≤50kg

7-15days

Fedex, DHL,UPS,TNT,EMS ect.

Fast and convenient

By Air

50kg~200kg

3-5days

Fast and cheap

By Sea

Large quantity

20-35days

Cheapest way

Lead time: Within 3 workdays after receiving payment.

Payment Term

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Why Choose Xi'an Yihui?

Customer feedback

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Xi'an Yihui certificates

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Xi'an Yihui Factory & Warehouse

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Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

In conclusion

To sum up, Xi 'an Yihui Company as a professional manufacturer of Acarbose API , with high-quality products, high level of research and development capabilities, advanced production equipment and technology, perfect after-sales service and other advantages, is the customer choice of the ideal partner.

if you need it, pls feel free to contact us any time. we will reply you ASAP.

Our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937

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