What is Iodixanol API?

Iodixanol API chemical name is Ioxaxol is 6 α- Fluoro-11 β, 21-dihydroxy-16 α- Isopropylidedioxy-1,4-pregnadiene-3,20-dione.The molecular formula is C35H44I6N6O15, and the CAS number is 92339-11-2. It's a White to out-white, unformed, odorless, hygroscopic powder, answerable in chloroform and ethanol, slightly answerable in dichloromethane and acetone, and undoable inwater.it is used for cone tube angiography, cardiocerebral angiography, and intravenous urography.The principle of its action is to combine iodine to absorb X-rays in blood vessels or tissues, resulting in image display. It has a lower impact on cardiovascular parameters and femoral blood inflow, but it should be taken into account when using it in senior cases with renal insufficiency witnessing coronary intervention.

The discovery and development of it can be traced back to the late 1980s and early 1990s.

In 1987, IBS Pharmaceuticals of the University of Oslo, Norway, began to conduct exploration on angiography and gradationally bettered and optimized the molecular structure of known non-ionic-ray discrepancy agents, similar as the sulfonate composites of ethylene glycol.In doing so, the researchers discovered a new compound called Iodixanol, which consists of iodine, benzoic acid, and cyclohexyl glycolic acid. Compared with other known X-ray contrast agents, the compound has better safety and tolerance and possesses better imaging quality, so it was quickly widely studied and developed.

In 1996, the European Centre for Liver Research in Norway, in collaboration with IBS, successfully developed a formulation of Iodixanol, which was used in clinical trials for the first time in Europe. In 1999, the medicine was approved for marketing by the European Union, making it the world's first commercially available next- generation nonionicX-ray discrepancy agent. Since also, It has also been extensively used around the world and has gradationally become a routine discrepancy agent for numerous clinical examinations and interventional surgeries.

Basic Information

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Fuctions & application 

Iodixanol API is a contrast agent based on the molecular structure of it. It consists of two main components,Iodixanol and iodine, which are obtained by combining the two.

It has good biocompatibility and high imaging sensitivity. It is often used in medical imaging for non-invasive diagnosis of various organs and blood vessels of the human body through imaging technology.

it is a widely used contrast agent in medical imaging with high imaging sensitivity and biocompatibility. Attention should be paid to patients' renal function and allergic reaction, as well as reasonable dose control, so as to achieve better imaging diagnosis effect.

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Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.

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 In conclusion

In summary, Xi'an Yihui company as a professional Iodixanol API manufacturer, has strong technical strength and advanced production equipment, and is committed to providing customers with high -quality, efficient and reliable drug raw materials. if you need it, pls feel free to contact us any time. we will reply you asap.

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