What is Chloroquine Diphosphate?

Chloroquine diphosphate belongs to the class of 4- aminoquinoline antimalarial medicines. It can inhibit the conflation of nucleic acids in Plasmodium, intrude with the growth and reduplication of the sponger, and effectively kill the schizonts in the erythrocytic stage of malaria. It can be used to treat nasty malaria, tertian malaria, quartan malaria, and can also be used for suppressive prophylaxis of malaria symptoms. It can also be used to treat extraintestinal amebiasis, connective towel conditions, and photosensitivity diseases( similar as sun- convinced erythema).

it is a white to pale unheroic crystalline or crystalline powder that's answerable in water and methanol. Its chemical formula is C18H26ClN3 · 2H3PO4, with a molecular weight of515.87 g/ spook, and the CAS number is 50-63-5. Chloroquine, as an antimalarial medicine, forms DNA crosslinks in an alkaline terrain and disrupts the metabolic exertion of the pathogen. It's an alkaline medicine that affects the conformation of acidic food vacuoles in spongers by inhibiting the polymerization of brim- suchlike composites. It can also alter the metabolic pathways of the pathogen by inhibiting the exertion of acid hydrolases and snooping with the declination of brim- suchlike composites.

Basic Information

Product name: Chloroquine diphosphate

CAS:50-63-5

MF: C18H32ClN3O8P2

MW:515.86

EINECS:200-055-2

MDL No.:MFCD00069852

Melting point:200℃

storage temp.: room temp.,protect from light

Stability: Stable

Structural formula:

Quality standard

Function &Application

Chloroquine diphosphate is mainly used in the following areas:

1. Antimalarial it's an effective antimalarial medicine used to treat sensitive cases of severe malaria, vivax malaria, and malariae malaria. It can inhibit the nucleic acid conflation of the malarial sponger, disrupt its growth and reduplication.

2. Immunomodulation it's also used as an immunomodulator for the treatment of autoimmune conditions similar as rheumatoid arthritis and lupus erythematosus. It can regulate the function of the vulnerable system, palliate seditious responses and autoimmune responses.

3. Antiviral exploration has shown that it has antiviral exertion against certain contagions. For illustration, it can effectively treat viral conditions similar as malaria, dengue fever, and Zika contagion. In addition, It has also been used in clinical treatment of COVID- 19, but it should be used with caution and under the guidance of a croaker .
   

4. Treatment of other conditions it's also used to treat other conditions similar as extraintestinal amebiasis, connective towel conditions, and photosensitivity diseases( similar as polymorphous light eruption). Although it may have some goods in the treatment of these conditions, the specific mechanisms and goods need farther exploration and evidence.

In summary, It is a protean medicine primarily used for antimalarial, immunomodulatory, and antiviral purposes. still, the specific lozenge and operation should be determined according to the advice of a croaker and the specific condition of the case. It's also important to be apprehensive of its adverse responses and contraindications.

Storage

The storage requirements for Chloroquine Diphosphate powder API are as follows:

1. Storage environment: It should be stored in a dry, well-ventilated, and cool place, away from direct sunlight and high temperatures.

2. Packaging container: It should be stored in a tightly sealed glass or plastic container.

3. Avoid moisture: It should be kept away from contact with water and humid environments to prevent discoloration due to moisture absorption.

4. Keep out of reach of children: It should be stored in a place where children cannot access it to prevent accidental ingestion or misuse.
   

In conclusion, It should be stored in a dry, cold, well-ventilated area that is free from moisture and vibration in order to maintain its quality and efficacy. Make sure the packaging container is secure and intact, and keep it out of children's reach. Drugs that have expired or are no longer working should be discarded right away.

Packing & Shipping

Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum;or packing as your request.

Customization:Customized logo;Customized packaging;Graphic customization

Shipping:

Lead time: Within 3 workdays after receiving payment.

Payment Term

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In conclusion, Chloroquine diphosphate should be stored in a dry, cold, well-voiced area that's free from humidity and vibration in order to maintain its quality and efficacity. Make sure the packaging vessel is secure and complete, and keep it out of children's reach. medicines that have expired or are no longer working should be discarded right down.

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