What is Entecavir hydrate?

Entecavir hydrate chemical name is( 1S, 4R)-2-Amino-1-( 4- hydroxy- 2-( hydroxymethyl) cyclopent-1-enyl)- 6-( 4- propyl-3-sulfonatopropoxy) quinazolin- 4( 3H)- one hydrochloride hydrate ， The chemical formula is C12H15N5O3 · H2O, CAS numer is 209216-23-9. It's a broad-diapason antiviral medicine, belonging to nucleoside rear transcriptase impediments. It's primarily used to treat hepatitis B contagion( HBV) infection, but can also be used to treat viral conditions such a hepatitis C contagion( HCV) infection.

The preparation method of Entecavir monohydrate is mainly divided into three steps:

Firstly, isopentane is used as a solvent to react Entecavir API with sodium hydroxide to get intermediates;

The intermediate was further replied with text-butoxy carbonyl isopropyl carbonate in N, n- dimethylformamide( DMF) to form a product;

3. The product was formed, filtered, and dried to gain Entecavir monohydrate with high chastity and stable quality. The medication system can ameliorate the yield and chastity, and is simple to operate, and has good technological parcels.

It's available in tablet or capsule form. In clinical use, Entecavir monohydrate can reduce symptoms of liver complaint, ameliorate liver function, and inhibit viral replication and infection.

Basic Information

Quality standard

Function & Application

Entecavir hydrate is a pharmaceutical raw material used to treat hepatitis B virus (HBV) infection. its efficacy and application:

Antiviral action It's a nucleoside analog that can inhibit the replication and spread of the hepatitis B contagion. It works by suppressing the exertion of the contagion's rear transcriptase, precluding the replication of the viral genome, thereby reducing the viral cargo and inhibiting viral replication.

Improves liver function Treatment with entecavir can effectively ameliorate liver function labels similar as hepatitis B contagion serology labels( HBsAg, HBeAg), and liver enzymes( ALT, AST) situations. It can palliate liver inflammation and help further liver damage.

Controls contagion rush It can suppress the rush of hepatitis B contagion. Long-term use can help maintain sustained repression of hepatitis B contagion DNA, reducing viral replication and the threat of hepatitis B contagion resistance.

Reduces the threat of liver cirrhosis and liver cancer development Treatment with entecavir can reduce the threat of progression to liver cirrhosis and liver cancer in individuals infected with hepatitis B contagion. By inhibiting viral replication, it can decelerate the progression of contagion-related liver complaints, thereby reducing the circumstance of liver cirrhosis and liver cancer.

operation compass It's suitable for the treatment of habitual hepatitis B contagion infection in grown-ups. It can also be used in certain special cases, such as pediatric hepatitis B contagion infection, pregnant women with hepatitis B contagion infection, or in the case of hepatitis B contagion medicine resistance. still, it should be used under the guidance of a croaker.

In summary, Entecavir API is an effective medication for the treatment of hepatitis B virus infection, with the benefits of antiviral action, improvement of liver function, control of virus recurrence, and reduction of the risk of liver cirrhosis and liver cancer development. However, its specific application scope should be determined based on individual patient conditions and medical professional advice. Please consult a doctor or other healthcare institution before use.

Packing & Shipping

Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.

Customization: Customized logo; Customized packaging; Graphic customization

Shipping:

Payment Term

Why Choose Xi'an Yihui?

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Xi'an Yihui Factory & Warehouse

Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

In conclusion

In summary, Xi'an Yihui company as a professional Entecavir hydrate manufacturer, has strong technical strength and advanced production equipment and is committed to providing customers with high-quality, efficient, and reliable drug raw materials. if you need it, pls feel free to contact us at any time. we will reply you ASAP.

Our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937

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