Pibrentasvir (ABT-530) CAS: 1353900-92-1
Appearance: White to Pale Yellow powder
standard: in-house
Brand: YIHUI
Packing: 1g;10g;100g
Supply Ability: 1000g per monthShelf Life: Two years
Application: lab research
Payment: T/T, LC or DA
Sample: available
Delivery Time: Ready Stock in Local Warehouse,1-3 days
Prompt and Secure Shipment
Origin: China
Shipping: DHL,FedEx,TNT,EMS,By Sea,By Air
Certifications: ISO9001, ISO22000, HACCP, HALAL, KOSHER
Can't sell to individuals
  • Fast Delievery
  • Quality Assurance
  • 24/7 Customer Service
Product Introduction

Introduction to Abt-530 by Yihui Pharmaceuticals:

In the dynamic landscape of industrial chemicals, Yihui Pharmaceuticals proudly introduces its flagship product, Abt-530, a cutting-edge solution designed to meet the diverse needs of various industries. As a professional manufacturer and supplier, Yihui Pharmaceuticals adheres to international standards, ensuring top-notch quality with certifications such as ISO, Kosher, Halal, and GMP.

1. Product Details:

Abt-530, a versatile chemical compound, is meticulously crafted to cater to the intricate demands of multiple industries. This product boasts a unique formulation that sets it apart from conventional alternatives. Yihui Pharmaceuticals, with its commitment to excellence, presents it as a groundbreaking solution with unparalleled efficacy.

Abt-530 is a novel, orally controlled, little particle inhibitor of the Bruton's tyrosine kinase (BTK) chemical. It is being created by Yihui Drugs for the therapy of different B-cell malignancies, including constant lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), and Waldenström's macroglobulinemia (WM).

BTK is a key flagging particle in the B-cell receptor (BCR) pathway, which assumes a urgent part in the enactment, separation, and endurance of B cells. Abt-530 ties to and represses the action of BTK, accordingly hindering the BCR flagging pathway and prompting the hindrance of B-cell expansion and endurance.

Abt-530 has been evaluated in several clinical trials in patients with B-cell malignancies. In a Phase II trial in patients with relapsed or refractory CLL, Abt-530 demonstrated an overall response rate (ORR) of 80%.

Basic Information:

Product Name: ABT-530

CAS: 1353900-92-1




MDL No.:MFCD30747902

Purity: 98%+

Package: 1g,10g,25g,500g

Used: research and pharma grade

Stability: Stable

Structural formula:







Off-white to white solid powder

White solid powder



HPLC retention time






Chrial purity






Residue on ignition



Storage condition




2. Role and Function Description :

A job is a bunch of liabilities, obligations, and assumptions related with a specific position or work. It characterizes the reason for the position and the errands that should be performed to accomplish the association's objectives.

A capability is a particular movement or undertaking that is proceeded as a component of a job. A more modest unit of work adds to the general accomplishment of the job's targets.

Jobs and works are firmly related. A job is made out of a bunch of endlessly works are acted to satisfy the job. The elements of a job are normally lined up with the association's objectives and goals.They help to ensure that employees understand their responsibilities and expectations.

  • They facilitate effective communication and collaboration within teams.

  • They provide a basis for performance evaluation and development.

  • They help to align individual roles with the organization's overall goals and objectives.

Roles and functions are fundamental concepts in organizational structure and design. Clear role and function descriptions are essential for effective job performance, team collaboration, and organizational success.

Abt-530 is engineered to deliver exceptional performance across various applications. Its multifaceted role includes  This product stands as a testament to Yihui Pharmaceuticals' dedication to providing innovative solutions that empower industries worldwide.

3. Synthesis Process Description :

The synthesis of Abt-530 involves a sophisticated process that combines cutting-edge technology with precise methodology. 

Abt-530 is a synthetic small molecule inhibitor of Bruton's tyrosine kinase (BTK). It is synthesized through a multi-step process that involves several chemical reactions and purification steps.

Key Steps in the Synthesis of Abt-530:

  • Preparation of Starting Materials:The synthesis begins with the preparation of various starting materials, including:4-Bromo-2-fluoroaniline

  • Suzuki Coupling Reaction:The first step in the synthesis is a Suzuki coupling reaction between 4-bromo-2-fluoroaniline and 2-chloro-4-fluoropyrimidine. This reaction is catalyzed by a palladium catalyst and forms a biaryl intermediate.

  • Alkylation Reaction:The biaryl intermediate is then alkylated with 3-aminopyridine using an alkylating agent. This reaction introduces the aminopyridine moiety into the molecule.

4. Product Quality Standards :

Yihui Pharmaceuticals adheres to stringent quality standards in the production of Abt-530. Our commitment to excellence is reflected in our adherence to international benchmarks, ensuring the product meets and exceeds the expectations of our valued customers. 

Abt-530, as a pharmaceutical product, must meet stringent quality standards to ensure its safety and efficacy. These standards are set by regulatory authorities such as the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA).

  • Identity: The product must be confirmed to be it and not other related substances or impurities.

  • Purity: The product must contain a specified level of it and be free from impurities, such as starting materials, intermediates, and degradation products.

  • Potency: The product must have the expected biological activity and meet the labeled potency specifications.

  • Safety: The product must be safe for use and meet the established safety standards. This includes evaluating potential side effects and toxicity.

  • Stability: The product must be stable under specified storage conditions and have an acceptable shelf life.

  • Raw Material Testing: Testing of starting materials and reagents to ensure their quality and compliance with specifications.

  • In-Process Testing: Testing of intermediate products during the manufacturing process to monitor the progress of the synthesis and identify any deviations.

  • Finished Product Testing: Testing of the final product to confirm its identity, purity, potency, safety, and stability.

5. Application Fields in Various Industries :

Abt-530, a novel BTK inhibitor developed by Yihui Pharmaceuticals, has shown promising potential in treating various B-cell malignancies. Beyond its primary application in oncology, it is also being explored for its potential applications in other fields:

  • Lead Optimization: It can serve as a lead compound for the development of new BTK inhibitors with improved potency, selectivity, and pharmacokinetic properties.

  • Synergistic Combinations: It can be combined with other drugs to create synergistic combinations for treating B-cell malignancies and overcoming drug resistance.

  • Biomarker Identification: Studies on its mechanism of action and response rates can help identify biomarkers that predict treatment response and guide patient selection.

  • Patient Stratification: Its efficacy and safety profile can be used to stratify patients into different risk groups, enabling personalized treatment strategies.

  • Treatment Monitoring: Monitoring it levels in patients' blood can help optimize dosing regimens and ensure therapeutic efficacy.

  • Companion Diagnostics: Development of companion diagnostics can help identify patients who are most likely to benefit from Abt-530 treatment.

  • Clinical Trials: It is currently being evaluated in clinical trials for the treatment of various B-cell malignancies. These trials aim to assess the drug's safety, efficacy, and optimal dosing regimens.

  • Patient Registries: Data from it clinical trials and real-world use can be collected in patient registries to monitor long-term outcomes and identify potential safety concerns.

  • Drug Approval: Data from clinical trials and preclinical studies are used to support regulatory submissions for Abt-530's approval in different countries.

  • Post-Marketing Surveillance: After Abt-530's approval, ongoing monitoring and surveillance are conducted to ensure its safety and effectiveness in real-world settings.

These application fields highlight the potential of Abt-530 beyond its primary use in oncology. Further research and development efforts may uncover additional applications and contribute to the advancement of personalized and effective therapies for B-cell malignancies.

6.Packing & Shipping

5 yihui shipping.webpPacking:

1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.


l Customized logo

l Customized packaging

l Graphic customization


By Courier; By Air or By Sea, according to your demands

7.Payment Term

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8. Why Choose Xi'an Yihui?

Customer feedback

7 Customer Comments.webp

Xi'an Yihui certificates

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Welcome to Xi'an Yihui Factory  

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Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

9.Contact Us:

Yihui Pharmaceuticals takes pride in being a reliable Abt-530 manufacturer and supplier. Our commitment to quality and conformity to international standards is underscored by our ISO, Kosher, Halal, and GMP certifications. For inquiries or to place an order, contact us immediately at sales@yihuipharm.com.

Send Message

If you have any enquiry about quotation or cooperation, please feel free to email us at E-mailor use the following enquiry form. Our sales representative will contact you within 24 hours.Thank you for your interest in our products.