Levomefolate Calcium Powder

Product name: Calcium L-5-Methyltetrahydrofolate
CAS No.: 151533-22-1
Packing:1kg/bag;5kg/drum; 25kg/drum
Supply Ability:500Kg per month
Used: Pharma grade, food grade or Cosmetics grade etc.
Delivery Time:in stock
Shelf Life: Two years
Payment: T/T, LC or DA
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Product Introduction

What is Levomefolate Calcium?

Levomefolate Calcium powder is the calcium swab of L-5-methyltetrahydrofolate, which belongs to the folate family of vitamins( Vitamin B9, folic acid) and is a coenzyme form of folate. L-5-methyltetrahydrofolate calcium( 5- MTHF), a naturally being swab- methyl secondary form of folate, is also known as L- methylfolate. It's the most biologically active and functional form of folate and is more fluently absorbed than regular folic acid. 

Folate insufficiency can reduce the capability to synthesize and repair DNA, and supplementing with folate may be a more favorable way to increase folate, lower homocysteine situations, and support normal cell proliferation and endothelial function in the cardiovascular system and neurological function. Specifically, supplementing with Levomefolate Calcium during gestation has been shown to reduce the threat of neural tube blights and rush.

Basic Information:

Product name: Levomefolate Calcium; L-5-Methyltetrahydrofolate calcium


MF: C20H27CaN7O6



MDL No.:MFCD18642975

Melting point:>300°C

storage temp.:
Inert atmosphere,2-8°C

Appearance:White to light yellowish crystalline powder

Stability: Stable for 2 years

Structural formula:


Quality standard:





White to light yellowish powder



Retention time matches that of a reference standard



(On dry basis)









Water (KF)




(On dry basis)




Confirmed with in-house standard

Storage conditions:

Keep in dry& cool place, keep away from strong sunlight.


Levomefolate Calcium powder, also known as Levomefolate Calcium or L- Methylfolate Calcium, is the synthetic form of folate and has the following uses

Folic acid supplementation L-5-Methyltetrahydrofolate calcium can be used as a supplement for folate to treat and help folate insufficiency diseases. Folate is an important vitamin that's pivotal for cell division, DNA conflation and form, and red blood cell conformation.

Antenatal care During gestation, women frequently need increased input of folate to support proper neural tube development in the fetus. L-5-Methyltetrahydrofolate calcium can be used as a folate supplement for pregnant women to reduce the threat of neural tube blights similar as spina bifida.

Cardiovascular health Folate helps lower the situations of homocysteine, which is associated with an increased threat of cardiovascular conditions. L-5-Methyltetrahydrofolate calcium can be used to lower homocysteine attention in the blood, thereby promoting cardiovascular health.

Antagonist to antifolate medicines Certain specifics, similar as the anticancer medicine methotrexate, may intrude with folate metabolism and application. L-5-Methyltetrahydrofolate calcium can be used as an cure to these antifolate medicines, helping to palliate their side goods.

Please note that the mentioned uses are general clinical applications, and specific use of L-5-Methyltetrahydrofolate calcium should be done under the guidance and prescription of a doctor.

Metabolic Pathways:

There are two main metabolic pathways in which regular folic acid must be converted to Calcium L 5 Methyltetrahydrofolate in order to share methylation processes and DNA conflation. The only form of folate that generally appears in the tube and intracellularly in the mortal body is 5- MTHF. Folate insufficiency is generally due to inadequate immersion caused by vitamin insufficiency, increased need for folate during gestation, lactation, and nonage growth, or changes in immersion or metabolism, as well as the incapability to guarantee the handed lozenge through consumption of folate-rich foods, therefore challenging supplementation.

Mechanism of Action:

The biochemical exertion of folate in metabolic pathways involves a series of enzyme- catalyzed responses andco-factors. Absorbed folate is reduced and methylated to form 5- MTHF during the process of metabolism in intestinal mucosal cells. This conversion is limited and doesn't alter the appearance of folate in the bloodstream. Homocysteine is latterly converted to S- adenosylmethionine( SAMe), a methyl patron that participates in multiple biochemical processes. It also serves as a methyl patron in nucleotide conflation, supporting the biosynthesis of DNA.

Packing & Shipping

Packing:1kg/foil bag;5kg/carton;25kg/fiber drum;or packing as your request.


Customized logo

Customized packaging

Graphic customization




ETA time

Shipping Method

By Courier



Fedex, DHL,UPS,TNT,EMS ect.

Fast and convenient

By Air



Fast and cheap

By Sea

Large quantity


Cheapest way

Lead time: Within 3 workdays after receiving payment.

Payment Term


Why Choose Xi'an Yihui?

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Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

In conclusion

In summary, as a professional Levomefolate Calcium powder manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make our Calcium L-5-Methyltetrahydrofolate stand out in the market competition and win more customer trust and support. if you need Levomefolate Calcium, pls feel free to contact us any time. we will reply you asap.

our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937

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