6-Aminocaproic Acid

Product name: 6-Aminohexanoic acid
CAS No.: 60-32-2
MOQ: 1kg
Assay: 99%
Packing: 1kg/bag;25kg/drum
Supply Ability: 10000kg per month
Used: medicine grade; industrial grade
Delivery Time:in stock
Shelf Life: Two years
Payment: T/T, LC or DA
Can’t sell to individuals
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Product Introduction

What is 6-Aminocaproic acid?

6-Aminocaproic acid, also known as Aminohexanoic acid, ε- aminocaproic acid, or tranexamic acid, has the chemical formula H2NCH2( CH2) 3CH2COOH. It has a CAS number of 60-32-2 and a molecular weight of131.18. It has a harsh flavor and is odorless, coming from ether as lush chargers. It melts at a temperature between 202- 207 °C( corruption). undoable in ethanol, ether, and chloroform, it's answerable in water and just hardly answerable in methanol. Its pK2 is10.75, while its pK1 is4.43. The alkaline KMnO4 result has the capability to oxidize it into adipic acid. When replied with HNO2, it forms 5- hexenoic acid and 4- hexenoic acid. It's converted to 6-ureidohexanoic acid by boiling it with urea and barium hydroxide result. Esters can be created when it reacts with alcohols( ROH), and acylating agents( RCOCl) can introduce acyl groups on the aminogroup.It can be made in two ways by hydrolyzing 6-( N- benzoylamino) hexanenitrile in the presence of hydrochloric acid, or by hydrolyzing caprolactam in the presence of hydrochloric acid and also treating the product with ammonium hydroxide.It serves as an antifibrinolytic agent and is employed in chemical conflation.

As a hemostatic agent, 6-Aminocaproic acid's used to treat severe bleeding brought on by elevated fibrinolysis and is relatively effective in doing so. During numerous procedures, it's suitable for oozing or original bleeding. also, it's employed in gynecology and obstetrics for hemoptysis, gastrointestinal bleeding, and bleeding disorders.A typical antifibrinolytic hemostatic drug is 6-aminohexanoic acid, frequently known as aminocaproic acid or epsilon- aminocaproic acid. By competitively blocking the activation of plasminogen activators and precluding the conversion of plasminogen to plasmin, it exerts antifibrinolytic conduct. It also slows the breakdown of fibrin into peptides and amino acids by having a weak direct inhibitory effect on plasmin. Blood must have a 6-aminohexanoic acid attention of 130 mg/ L or advanced to help plasminogen from turning into plasmin, and blood must have a attention of 1300 mg/ L or advanced to help plasmin from acting directly, which prevents fibrin from dissolving and results in hemostasis.

Its activity lasts quite briefly and has a mild, quick-elimination impact.With an 80% bioavailability after oral administration, it is quickly and thoroughly absorbed in the digestive system. After consumption, peak blood concentrations are obtained in under two hours. Its half-life is approximately 103 minutes, and the majority of it is eliminated intact in the urine.


Basic Information

Product name: 6-Aminohexanoic acid

CAS:60-32-2

MF: C6H13NO2

MW:131.17

EINECS:200-469-3

MDL No.:MFCD00008238

Storage Temperature: Store below +30°C.

Stability: Stable

Structural formula:

60-32-2.webp

Quality standard

Item

Specification

Results

Character

White crystalline powder.

White crystalline powder.

Freely soluble in water, almost insoluble in ethanol and and chloroform or ether.

Conforms

Melting point

204~207C

204.0~~204.5℃

Identification

The Infrared absorption spectrum is concordant with the reference spectrum.

Conforms

Clarity of solution

Should be conform

Conforms

pH

7.5~8.0

7.9

Sulfate

NMT 0.01%

Conforms

Calciumion

Should be conform

Conforms

Chloride

NMT 14ppm

Conforms

Loss on drying

NMT 0.5%

0.06%

Water by KF

NMT 0.5%

0.1%

Residue on ignition

NMT 0.1%

0.03%

Heavy metals

NMT 10ppm

Conforms

Arsenic salt

NMT 2ppm

Conforms

Bacterial endotoxin

<0.5EU/mg

Conforms

Microbial limit

Total aerobic bacteria:≤1000cfu/g

<10cfu/g

Molds and yeasts:≤100cfu/g

<10cfu/g

Escherichia coli: Negative

Negative

Absorbance

287nm, no more than 0.10

450nm, no more than 0.03

287nm, 0.041

450nm, 0.007

287nm, no more than 0.15

450nm, no more than 0.03

287nm, 0.125

450nm, 0.011

Assay

≥98.5% on drying basis

99.4%

Function and application

It serves a variety of purposes and has the following applications:

  • Hemostatic agent An important hemostatic medicine, It prevents fibrinolysis, slows down the breakdown of fibrinogen, and increases the stability of blood clots. It's used to treat a variety of bleeding conditions, similar as upper gastrointestinal bleeding, surgical bleeding, traumatic bleeding, and gynecological bleeding.

  • Antifibrinolytic agent Aminocaproic acid is an antifibrinolytic medicine that can reduce fibrinogen declination by blocking the conversion of plasminogen to plasmin. This quality makes it useful for treating bleeding brought on by hyperfibrinolysis.

  • Antifibrinolytics agentIncreased fibrinogen dissolving exertion may do in some conditions or following surgery, exacerbating the liability to hemorrhage. It can be used as an antifibrinolytic to help fibrinogen from breaking down and to manage bleeding.

  • Effect on inflammation According to certain exploration, It has the capability to suppress seditious responses and the release of seditious intercessors. It demonstrates pledge in the operation of several seditious ails.

  • Antitumor effect: Aminocaproic acid may have inhibitory effects on tumor growth and metastasis, exhibiting specific anticancer effectiveness against specific forms of cancer, according to some research. Further research is necessary to determine the particular anticancer mechanism, though.

A versatile substance with significant uses in hemostasis, antifibrinolysis, anti-inflammation, and perhaps anticancer actions, It is summarized above. However, particular dosages and usage strategies should be decided upon taking into account each patient's unique situation and expert medical assistance. Prior to use, please speak with a physician or pharmacist.

Stability & storage

When kept under the right conditions, aminocaproic acid, also known as 6-aminohexanoic acid, is often stable. The stability and storage recommendations for 6-aminohexanoic acid are as follows:

  • Temperature: 6-Aminohexanoic acid should be kept between 20°C and 25°C (68°F and 77°F) at room temperature.

  • Moisture: Prevent excessive moisture from damaging the substance. It is better to keep it in a container that is completely sealed.

  • Light: Avoid exposing 6-aminohexanoic acid for an extended period of time to intense light sources or direct sunlight. Keep it in a container that is dark or opaque.

  • Incompatible substances: contrasting substances To prevent deterioration, keep 6-aminohexanoic acid away from or incompatible materials such oxidizing agents, potent acids, or bases.

  • package: To preserve its stability, 6-aminohexanoic acid should be kept in its original package or a tightly sealed container.


Packing & Shipping

Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.

Customization: Customized logo; Customized packaging; Graphic customization

Shipping:

Item

Quantity

ETA time

Shipping Method

By Courier

≤50kg

7-15days

Fedex, DHL,UPS,TNT,EMS ect.

Fast and convenient

By Air

50kg~200kg

3-5days

Fast and cheap

By Sea

Large quantity

20-35days

Cheapest way

Payment Term

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Customer feedback

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Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

In conclusion

In summary, as a professional 6-Aminocaproic acid manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make our Aminohexanoic acid stand out in the market competition and win more customer trust and support. if you need it, pls feel free to contact us any time. we will reply you asap.

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