Sorafenib Tosylate

CAS: 475207-59-1
Appearance: White to off-white Powder
standard: in-house
Package: 10g;100g;1kg
Supply Ability: 300kg per month
Shelf Life: Two years
Application: Antitumor, Anticancer or lab research
Payment: T/T, LC or DA
Sample: available
Delivery Time: Ready Stock in Local Warehouse,1-3 days
Prompt and Secure Shipment
Origin: China
Shipping: DHL,FedEx,TNT,EMS,By Sea,By Air
Certifications: ISO9001, ISO22000, HACCP, HALAL, KOSHER
Can't sell to individuals
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Product Introduction

What is Sorafenib Tosylate?

Sorafenib Tosylate belongs to a class of drugs known as multikinase inhibitors, which work by inhibiting the activity of proteins involved in cancer cell growth and survival.

Sorafenib Tosylate, a cutting-edge pharmaceutical compound, stands as a testament to Yihui's commitment to excellence in drug manufacturing. At Yihui, we take pride in being a professional product manufacturer and supplier, meeting the rigorous standards set by international certifications such as ISO, Kosher, Halal, and GMP.


Basic Information

Product Name: Sorafenib Tosylate

CAS: 475207-59-1

MF:C21H16ClF3N4O3.C7H8O3S

MW:637.03

EINECS:641-758-8

MDL No.:MFCD08235032

Purity: 99%

Package: 1KG; 25Kg

Used: pharma grade & Lab research

Stability: Stable

Structural formula:

475207-59-1.webp

Specifications and Parameters:

Let's delve into the specifics of the product with a comprehensive table highlighting its key specifications and parameters.

Items

Specifications

Results

Appearance

Off-White or white powder

Off-White powder

Identification

H-NMR, MS

Complies

Melting Point

222.0 ~ 226.0

224.5~225.5

Residue on ignition

≤0.5%

0.03%

Loss on Drying

≤ 1.0%

0.17%

Heavy metals

≤20ppm

Complies

Related Impurity by HPLC

Single impurity ≤0.10%

Total impurity≤0.5%

0.03%

0.08%

Purity (HPLC)

NLT 99.5%

99.92%

Chemical Composition:

Understanding the core elements of the product is crucial for appreciating its pharmacological properties. Here is a breakdown of its chemical composition.

ComponentPercentage Composition
Sorafenib Tosylate100%

Role and Function:

As a pharmaceutical compound developed for the treatment of cancer, the product has gained recognition for its multifaceted pharmacological effects. Its primary mechanism of action involves inhibiting key signaling pathways within cancer cells, making it a highly effective kinase inhibitor.

One of the major pathways targeted by CAS 475207-59-1 is the RAF/MEK/ERK pathway. By inhibiting this pathway, the drug disrupts the signaling cascade that promotes cell growth and division, ultimately leading to the inhibition of tumor cell proliferation. Additionally, the product also targets the VEGFR/PDGFR pathway, which plays a crucial role in angiogenesis, the process of blood vessel formation. By blocking this pathway, the drug effectively impedes tumor angiogenesis, depriving the cancer cells of oxygen and nutrients necessary for their survival and growth.

The anti-angiogenic effects of the product extend its therapeutic potential beyond its direct anti-cancer properties. By suppressing the growth of blood vessels that nourish tumors, the drug can effectively limit the spread and progression of cancer. This dual inhibition of both cancer cell proliferation and tumor angiogenesis makes the product a valuable asset in the treatment of various types of cancer, particularly hepatocellular carcinoma and renal cell carcinoma.

Furthermore, CAS 475207-59-1 exhibits immunomodulatory effects, which contribute to its overall therapeutic efficacy. It enhances the body's natural defense mechanisms against cancer cells by stimulating immune responses and promoting the activation of immune cells. This immunomodulatory activity further assists in targeting and eliminating cancer cells, complementing its direct anti-cancer and anti-angiogenic effects.

Synthesis Process:

The synthesis process of Sorafenib Tosylate is a meticulously orchestrated series of chemical reactions. Starting with the reaction of 4-chloro-3-(trifluoromethyl)aniline with 4-nitrophenol, it undergoes subsequent transformations, involving protection, deprotection, and condensation steps. The final product emerges through crystallization, ensuring purity and potency.

Quality Standards:

Yihui's dedication to quality is evident in the product meeting the highest industry standards. Our manufacturing processes adhere to international guidelines, ensuring a product that surpasses purity levels of 99%. Rigorous testing for stability, solubility, and other critical parameters guarantees a reliable and effective pharmaceutical product.

Application Fields in Various Industries:

The product finds applications across diverse industries, with its primary focus in the pharmaceutical sector for cancer treatment. Its anti-angiogenic properties also make it relevant in research and development related to vascular disorders. As an essential ingredient in targeted therapy, it plays a pivotal role in improving patient outcomes in oncology.

OEM Services:

Yihui not only excels in the production of the product but also offers OEM services. This means we collaborate with businesses looking to market this pharmaceutical under their brand, providing customization options to meet specific requirements.

Contact Us:

Yihui stands at the forefront of Sorafenib Tosylate manufacturing, ensuring unparalleled quality. Our adherence to international standards and certifications such as ISO, Kosher, Halal, and GMP reflects our unwavering commitment to excellence. For those seeking a reliable supplier of the product, contact us at sales@yihuipharm.com.

In conclusion, the product embodies Yihui's dedication to advancing healthcare solutions, offering a potent weapon in the fight against cancer while upholding the highest standards of quality and manufacturing excellence.

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If you have any enquiry about quotation or cooperation, please feel free to email us at E-mailor use the following enquiry form. Our sales representative will contact you within 24 hours.Thank you for your interest in our products.

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