We supply Leucovorin Calcium

We offer Calcium folinate, a medication used to reduce the side effects of chemotherapy drugs and improve their effectiveness. Also known as leucovorin calcium, it is often used in the treatment of certain types of cancer, including colorectal cancer. Our Calcium folinate is manufactured in accordance with strict quality assurance guidelines and can be supplied in various forms and packaging options. Our knowledgeable team is available to assist with any questions or concerns you may have about this product.

What's Calcium folinate?

Calcium folinate is a detoxifying agent for folic acid antagonist drugs, also known as Folinic Acid Calcium Salt, Leucovorin Calcium , calcium giant folic acid, calcium hydrogen folic acid, ethyl aceticate, calcium tetrachide, and calcium -hydrogenate. Or there is no fixed powder, no smell. It is easy to dissolve in water, almost insoluble in ethanol or ether, and easily soluble in sodium hydroxide solution. Calcium folic acid is a metharocolidal derivative of folic acid, which is similar to folic acid and is the activation form of folic acid in the body. After entering the human body, the transformation of tetrahydrofolate enzyme transforms into tetrahydrogen folic acid can effectively combat the toxic response caused by amotomotlanxifraxitate. Calcium folic acid has a toxic reaction of "rescue" excessive folic acid antagonism in the body, which is conducive to the synthesis of thymine, DNA, RNA, and even protein. it can stimulate white blood cells to grow and mature. This product can limit the degree of damage to normal cells by methotrexate, and can reverse methalotate to bone marrow and gastrointestinal mucosa through mutual competitive effects, but it has no effect on existing meticotrotoxic neurotoxicity Essence It is mainly used as a detoxification agent of folic acid antagonist (such as methotrexate, aminotrexide, phenytoin, phenobab, ethomyeidine, or metharochemidine). When oral folic acid has poor effect, it is used for giant cellular anemia caused by oral diarrhea, malnutrition, pregnancy or infantile period, and leukocytosis. But it is not applicable to the deficiency of sexual anemia for vitamin B12. In recent years, calcium folic acid is used as auxiliary therapy for colon and rectal cancer. It is combined with fluoropicidine, which can extend the survival period.

Basic Information

Product Name: Calcium folinate

CAS:1492-18-8

MF:C20H25CaN7O7

MW:515.54

EINECS:216-082-8

MDL No.:MFCD08704249

Purity: 99%+

MOQ: 1kg

Origin: China

Application: Used for Scabies Skin Itchy

Delivery Time: 3-7days

Structural formula:

Melting point: >300°C

Storage conditions: Keep in dark place, Inert atmosphere, Room temperature

Solubility: Slightly soluble in water, almost insoluble in acetone and ethanol (96%).

Technical Specification:

Package:

1kg/bag; 25kg/drum

Safety Information

Dangerous goods label: Xn

Hazard category code: 36/37/38-42/43

Safety instructions: 26-36-36/37-22-45

WGK Germany: 3

RTECS number: MA0600500

F: 3-8-10-23

Customs code: 29362900

Stability: Hygroscopy

What is the function of Calcium folinate

Calcium folinate, also known as folinic acid, is a type of medication that is commonly used in the treatment of certain types of cancer. It is a form of folate, which is a type of B vitamin that is essential for the proper functioning of the body's cells and tissues.

The primary function is to help protect the body's healthy cells from the toxic effects of chemotherapy. By providing the body with additional folate, it can help reduce the risk of side effects such as mouth sores, diarrhea, and nausea.

Leucovorin Calcium is also used in the treatment of anemia caused by deficiencies in folate or vitamin B12. It can help increase the production of red blood cells and improve symptoms such as fatigue, weakness, and shortness of breath.

In addition to its medical uses, folinate calcium is also sometimes used in dietary supplements as a way to boost the body's levels of folate. This can be useful for individuals who are not getting enough folate through their diet or who have trouble absorbing folate due to medical conditions such as celiac disease or inflammatory bowel disease.

Overall, it is an important medication that can help support the health and well-being of individuals undergoing cancer treatment or experiencing folate deficiencies. Its ability to protect healthy cells and boost the body's levels of important nutrients makes it a valuable tool in the fight against cancer and other health conditions.

What is the application of Calcium folinate

Folinic Acid Calcium Salt is a pharmaceutical drug mainly used as a rescue therapy in cancer chemotherapy and overdoses of methotrexate.

1. Mainly used as an antidote for folic acid antagonists such as methotrexate, pyrimidine, or trimethoprim.

2. Used to prevent severe toxic effects caused by excessive or high-dose treatment with methotrexate.

3. Megaloblastic anemia caused by folate deficiency.

When used in combination with fluorouracil, it is used to treat advanced colon and rectal cancer.

5. Used to relieve toxic reactions caused by excessive levels of aminopterin and methotrexate, and can also be used to treat giant red blood cell anemia.

6. It counteracts the effect of folate antagonists, which bind to folate dehydrogenase to prevent the conversion of folate to tetrahydrofolate. In medicine, it is used to reduce the toxicity of methotrexate after chemotherapy. It also enhances the cytotoxic effect of 5-fluorouracil in anti-cancer.

7. it can counteract the effects of folic acid antagonists, which act by binding to dihydrofolate reductase and blocking the conversion of folic acid to tetrahydrofolate. In medicine, it is used to reduce the toxicity of methotrexate after treatment.

Overall, it is an essential drug in cancer chemotherapy and overdose management, as it has proven to be effective in enhancing the effectiveness of chemotherapy drugs and reducing their toxicity, thereby improving the quality of life of cancer patients.

Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

In conclusion

In summary, Xi'an Yihui company as a professional Calcium folinate produced manufacturer, has strong technical strength and advanced production equipment, and is committed to providing customers with high-quality, efficient and reliable drug raw materials. if you need it, pls feel free to contact us any time. we will reply you asap.

our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937