Marbofloxacin api

CAS: 115550-35-1
Appearance: Light yellow, crystalline power
Standard: EP
Shelf Life: Two years
Payment: T/T, LC or DA
Delivery Time: Ready Stock in Local Warehouse, 1-3 days
Prompt and Secure Shipment
Origin: China
Shipping: DHL, FedEx, TNT, EMS, By Sea, By Air
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Product Introduction

We supply Marbofloxacin api

We're proud to offer Marbofloxacin API, a largely effective antibiotic for treating bacterial infections in creatures. It works by inhibiting bacterial DNA replication and is especially effective against Gram-negative bacteria. Our product is of the loftiest quality and is manufactured to the loftiest assiduity norms. It's suitable for use in the product of veterinary drugs and can be customized to meet your specificrequirements.However, look no further than our Marbofloxacin powder, If you are looking for a dependable and effective result for the treatment of bacterial infections in creatures.

 

What is Marbofloxacin API

Marbofloxacin is a broad- diapason antibiotic that belongs to the fluoroquinolone class of antimicrobial specifics. It's generally used in veterinary drug to treat bacterial infections in creatures. It's a potent bactericidal medicine that works by inhibiting the exertion of bacterial DNA gyrase, which is essential for DNA replication, recap, and duplication.

It can be used to manufacture different specifics that are specified for colorful bacterial infections in creatures. The API is produced through a rigorous process of conflation, sanctification, and characterization to insure its quality and effectiveness. It's a white crystalline greasepaint that's answerable in water and organic detergents.

One of the primary advantages is its broad- diapason of exertion against colorful gram-negative and gram-positive bacteria, including those that are resistant to other antibiotics. The drug is generally specified to treat infections in the respiratory system, urinary tract, skin, and soft apkins.

Marbofloxacn API is a potent antibiotic that's generally used in veterinary drug to treat bacterial infections in creatures. It's effective against a broad diapason of bacteria, making it a useful drug in the operation of colorful contagious conditions. still, it should be used with caution and only as specified by a veterinarian to help the development of bacterial resistance and insure its safe and effective use.

 

Basic Information

Product Name: Marbofloxacin

CAS:115550-35-1

MF:C17H19FN4O4

MW:362.36

EINECS:640-416-5

MDL No.:MFCD00864820v

Purity: 99%+

Origin: China

Stability: Stable

Structural formula:

product-1-1

Melting point: 268-269 ℃ (dec.)

Boiling point: 571 ℃

Density: 1.55 ± 0.1g/cm3 (Predicted)

Flash point: >110 ° (230 °F)

Solubility: soluble in chloroform (slightly heated)

 

Technical Specification:

Determinations

Specifications

Results

Appearance

Light yellow, crystalline power

Complies

Solubility

-Water

-Methylene chloride

-Ethanol (96%)

 

Slightly soluble

Sparingly soluble

Very slightly soluble

 

Complies

Complies

Complies

Identification

-I.R. Spectrum

Concordant with the spectrum of reference substance

Complies

Absorbance

≤0.20

0.08

 

 

Related substances (%)

 

 

Impurity A

≤0.1

Not detected

Impurity B

≤ 0.1

Not detected

Impurity C

≤0.2

Not detected

Impurity D

≤0.2

Not detected

Impurity E

≤0.2

Not detected

Unspecified Impurity

≤0.2

0.07

Total Impurity

≤0.5

0.16

Heavy metals (ppm)

≤20

<20

Loss on drying (% w/w)

≤ 0.5

0.04

Sulphated ash (% w/w)

≤0.10

0.02

Assay (%w/wDried substance)

99.0~101.0

99.8

Residual

solvents

Ethanol(ppm)

≤5000

236

Dichloromethane(ppm)

≤600

Not detected

Conclusion: Complies with Ph Eur

Packaging: 1kg/bag; 25kg/drum

Storage conditions: room temperature, light proof, moisture-proof, sealed and dry

Transportation conditions: Transportation at room temperature

 

Security information

Dangerous goods label: Xi

Hazard category code: 52/53-36/37/38

Safety instructions: 61-36-26-60

WGK Germany: 2

RTECS number: UU8815140

Customs code: 29349990

 

What is the application of Marbofloxacn API?

Fluoroquinolone antibiotics are used to treat deep and superficial skin infections, urinary tract infections in dogs, skin and soft tissue infections in cats, and acute upper respiratory tract infections.

Used for respiratory, digestive, urinary tract, and skin infections caused by sensitive bacteria in cattle, pigs, dogs, and cats. It also has a therapeutic effect on bovine and sheep mastitis, as well as porcine mastitis uterine inflammation milk syndrome.

 

Pharmacology

Marbofloxacin API belongs to the class of fungicides, and its bactericidal activity is concentration dependent. Sensitive bacteria can die within 20-30 days after exposure. Like other fluoroquinolone drugs, maprofloxacin exhibits significant post antibiotic effects on both Gram negative and positive bacteria, and is active in both the stationary and growth phases of bacterial replication. Its mechanism of action is not fully understood, but it is believed that it can function by inhibiting bacterial DNA cyclooxygenase (type II topoisomerase), preventing the formation of DNA super helices and DNA synthesis. Mapofloxacin and other veterinary commercialized fluoroquinolone drugs have similar antibacterial activity profiles. These drugs have good activity against most Gram negative bacteria and cocci, including most species and strains of Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Enterococcus, Campylobacter, Shigella, Salmonella, Aeromonas, Haemophilus, Proteus, Yersinia, Vibrio, etc. Other commonly sensitive bacteria include Brucella, Chlamydia trachomatis, Staphylococcus (including penicillinase producing and methicillin-resistant bacteria), Chlamydia, and Mycobacterium. Fluoroquinolone drugs have varying activity against most Streptococcus species and are generally not recommended for the treatment of this bacterial infection. These drugs have weak activity against most anaerobic bacteria and cannot effectively treat anaerobic bacterial infections. Due to mutations, drug-resistant strains have emerged, especially Pseudomonas, Klebsiella pneumoniae, Acinetobacter, and Enterococcus, but it is generally believed that plasmid mediated resistance rarely occurs.

 

Biological activity

Marbofloxacin powder is an effective antibiotic that inhibits bacterial DNA replication.

 

In vitro research

It is a Fluoroquinolone antibacterial reagent specifically designed for veterinary use. It acts on broad-spectrum aerobic Gram negative and some Gram positive bacteria, as well as the genus Mycoplasma, and has high bactericidal activity. As a third-generation Fluoroquinolone, it mainly targets replication and transcriptase, such as DNA helicase and topoisomerase IV, both of which are crucial for bacterial survival. It significantly kills the pre flagella and intracellular flagella of Leishmania parasites, and this effect is dose-dependent and more effective than glucosamine antimonate and sodium antimonate. After treatment with Marbofloxacin, macrophages acquire anti infection ability and increase it through the NO synthase pathway. Strong anti Leishmania activity.

 

In vivo research

In vivo, it  treated Mhyopneumoniae 116 wild-type strain and clone re isolated strain at therapeutic doses for 4 days, exhibiting mycoplasma positive effects in logarithmic phase rather than lag phase. it treated at therapeutic doses, does not eliminate M. hyopneumoniae. 87.5% to 100% of pigs still show positive results after testing and cannot effectively reduce clinical symptoms. However, it treatment seems to reduce lung injury. it treatment at a dose of 6mg/kg in the tissue structure of horses infected with Staphylococcus aureus, once daily for 7 days, cannot effectively eliminate Staphylococcus aureus infection from hidden sites.

 

In conclusion

In summary, as a professional Marbofloxacin APImanufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need Marbofloxacin powder, pls feel free to contact us any time. we will reply you asap.

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E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
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